STUDENTS

Ph.D. Trainees

Lilian van Vlerken

E-mail:
Department: Pharmaceutical Sciences
Advisor: Mansoor Amiji

Biography

Projects

Presentations

  • Modulation of Multidrug Resistance in Cancer with Polymer Blend Nanoparticles, Lilian van Vlerken, Z. Duan, S. Little, M. Seiden, R. Langer, Mansoor Amiji, Northeastern University Research and Scholarship Expo 2007, Boston, MA, Mar 2007
  • Overcoming Cancer Multidrug Resistance via a Novel Multifunctional Therapeutic Approach Mediated by Polymer-blend Nanoparticles, Lilian van Vlerken, S Little, Z Duan, M Seiden, R Langer, Mansoor Amiji, 2006 AAPS Annual Meeting and Exposition, San Antonio, TX, Oct 2006
  • Modulation of Multidrug Resistance in Cancer with Polymer Blend Nanoparticles, Lilian van Vlerken, S Little, Z Duan, M Seiden, R Langer, Mansoor Amiji, NCI Nanotechnology Alliance Investigators Meeting, San Diego, CA, Oct 2006
  • Modulation of Intracellular Ceramide Using Polymeric Nanoparticles to Overcome Multidrug Resistance in Cancer Cells, Lilian van Vlerken, Z Duan, M Seiden, Mansoor Amiji, 2006 ISPE Annual Meeting, Orlando, FL, Oct 2006
  • Overcoming Cancer Multidrug Resistance via a Novel Mutifunctional Therapeutic Approach Mediated by Polymer-blend Nanoparticles, Lilian van Vlerken, Z. Duan, S. Little, M. Seiden, R. Langer, Mansoor Amiji, IGERT Project Meeting 2006, Northeastern University, Boston, MA, May 2006
  • Modulation of Intracellular Ceramide using Polymeric Nanoparticles to Overcome Multidrug Resistance in Tumor Cells, Lilian van Vlerken, Dinesh Shenoy, Z. Duan, M. Seiden, S. Mehta, Mansoor Amiji, Northeastern University Research and Scholarship Expo 2006, Northeastern University, Boston, MA, Mar 2006
  • Design and Development of a Polymer-Blend Nanoparticle Drug Delivery System to Overcome Multidrug Resistance in Cancer, Lilian van Vlerken, Controlled Release Society, Long Beach, CA
  • Modulation of Intracellular Ceramide using Polymeric Nanoparticle to Overcome Multidrug Resistance in Cancer Cells, Lilian van Vlerken, ISPE, Orlando, FL
  • Modulation of Multidrug Resistance in Cancer with Polymer Blend Nanoparticles, Lilian van Vlerken, NCI meeting, San Diego, CA

Publications

  • Augmentation of therapeutic efficacy in drug resistant tumor models using ceramide co-administration in temporal-controlled polymer-blend nanoparticle delivery systems, van Vlerken, L.E., Duan, Z., Little, S.R., Seiden, M., and Amiji, M.M., The AAPS Journal, V.DOI: 10.1208/s12248-010-9174-4, P. (2010)
  • Evaluations of combination mdr-1 gene silencing and paclitaxel administration in biodegradable polymeric nanoparticle formulations to overcome multidrug resistance in cancer cells, Yadav, S., *van Vlerken, L.E., Little, S.R., and Amiji, M.M., Cancer Chemotherapy and Pharmacology, V.63(4), P.711-722 (2009)
  • Multifunctional Polymeric Nanosystems for Tumor-Targeted Delivery, Padmaja Magadala, Lilian E. van Vlerken, Aliasgar Shahiwala and Mansoor M. Amiji, V. Torchilin (Ed), Multifunctional Pharmaceutical Nanocarriers: Development of the Concept, New York, NY: Springer Publishing, V., P.33-66 (2008)
  • Multi-functional nanocarriers to overcome tumor drug resistance, L. Jabr-Milane, L. van Vlerken, S. Yadav, M. M. Amjii, Cancer Treatment Reviews, V.34(7), P.592-602 (2008)
  • Multi-functional nanocarriers for targeting delivery of drugs and genes, L. Jabr-Milane, L. van Vlerken, H. Devalapally, D. Shenoy, S. Kommareddy, M. Bhavsar, M. M. Amiji, Journal of Controlled Release, V.130(2), P.121-128 (2008)
  • A Multi-Functional Polymeric Nanoparticle Strategy for Modulation of Drug Resistance in Cancer., Lilian E. van Vlerken and Mansoor M. Amiji , Pharmaceutical Engineering, V.27, P.0 (2007)
  • Modulation of Intracellular Ceramide using Polymeric Nanoparticles to Overcome Multi-Drug Resistance in Cancer., Lilian E. van Vlerken, Zhenfeng Duan, Michael V. Seiden, and Mansoor M. Amiji, Cancer Research, V.67, P.4843 (2007)
  • Poly(ethylene glycol)-modified Nanocarriers for Tumor-targeted and Intracellular Delivery., Lilian E. van Vlerken, Tushar K. Vyas, and Mansoor M. Amiji , Pharm Research, V., P.0 (2007)
  • Poly(ethylene glycol)-modified Nanocarriers for Tumor-targeted and Intracellular Delivery, Lilian van Vlerken, Tushar Vyas, and Mansoor Amiji, Pharm Research, DOI: 10.1007/s11095-007-9284-6, V., P. (2007)
  • Modulation of Intracellular Ceramide using Polymeric Nanoparticles to Overcome Multi-Drug Resistance in Cancer, Lilian van Vlerken, Z. Duan, M. Seiden and Mansoor Amiji, Cancer Research, V.67, N. 10, P.4843 (2007)
  • A Multifunctional Polymeric Nanoparticle Strategy for Modulation of Drug Resistance in Cancer, Lilian van Vlerken and Mansoor Amiji, Pharmaceutical Engineers - Journal of the International Society of Pharmaceutical Engineers, V.27, N. 3, P.1 (2007)
  • Multifuncational polymer blend nanoparticles for temporal-controlled release of combination therapeutics to overcome multidrug resistance of cancer, L. E. van Vlerken, Z. Duan, S. Little, M. V. Seiden, R. Langer, M. M. Amiji, The AAPS Journal, V.9: S2, P. (2007)
  • Design and Development of a Polymer-Blend Nanoparticle Drug Delivery System to Overcome Multidrug Resistance in Cancer, L. E. van Vlerken, Z. Duan, S. Little, M. V. Seiden, R. Langer, M. M. Amiji, Proceedings of International Symposium on the Controlled Release of Bioactive Materials, V., P. (2007)
  • Multifunctional polymeric nanoparticles for tumor-targeted drug delivery., Lilian E. van Vlerken and Mansoor M. Amiji , Expert Opinion in Drug Delivery, V.3, P.205 (2006)
  • Multi-functional Polymeric Nanoparticles for Tumour-targeted Drug Delivery, Lilian van Vlerken and Mansoor Amiji, Expert Opinion Drug Delivery, V.3, N. 2, P.205 (2006)
  • Polymeric nanosystems for site-specific drug and gene delivery, M. M. Amiji, L. van Vlerken, H. Devalapally, D. Shenoy, S. Kommareddy, M. Bhavsar, European Journal of Clinical Nanomedicine, V.(Invited review publication in the inagural journal issue based on "2008 European Journal of Clinica, P. ()

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